If depression has continued despite multiple medications, that’s not a personal failure — it’s a signal that your brain chemistry may need a different approach. Fuse Mind & Body provides SPRAVATO® (esketamine) and ketamine therapy for adults near Rye, NY, using a clinical, safety-first model with structured evaluation, in-office treatment, and ongoing follow-up.
Our clinic is based in New Rochelle, making advanced depression care accessible to Rye residents without long city commutes. Patients receive physician-led assessments, individualized protocols, and attentive monitoring in a calm, private setting.
Who SPRAVATO® Is For
You may be a candidate for evaluation at Fuse Mind & Body if you’re an adult near Rye, NY and have been dealing with:
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Ongoing depression that hasn’t responded well to standard antidepressants (Treatment-Resistant Depression)
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Persistent low mood, poor sleep, mental fog, loss of motivation, or anxiety that interferes with daily life
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A sense of being “stuck” after trying multiple therapies without meaningful improvement
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The need for a medically supervised, structured treatment option with real monitoring and follow-up
If you are experiencing a mental health emergency or thoughts of self-harm, call 988 (Suicide & Crisis Lifeline) or go to the nearest emergency room immediately.

SPRAVATO® vs. Ketamine: What’s the Difference?
Both SPRAVATO® (esketamine) and ketamine therapy are used in advanced depression care — but they are not the same treatment, and they serve different clinical needs.
SPRAVATO® (Esketamine)
SPRAVATO® is an FDA-approved nasal spray prescribed alongside an oral antidepressant for adults with treatment-resistant depression and, in some cases, major depressive disorder with suicidal thoughts.
At Fuse Mind & Body, SPRAVATO® is administered in-office under direct medical supervision, with required post-dose monitoring to ensure safety, comfort, and proper response.
Many Rye-area patients pursue SPRAVATO® when traditional medications have not provided enough relief and a regulated, FDA-approved option is preferred.
Ketamine Therapy
Ketamine has been used safely in medicine for decades and is offered in clinical settings for depression-related conditions under structured provider supervision.
Ketamine therapy is often chosen by patients seeking:
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A fast-acting treatment option
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A personalized dosing and maintenance protocol
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Care delivered in a monitored, in-office medical environment
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Treatment plans vary by patient and are always based on individual evaluation and safety considerations.
What Treatment Looks Like at Fuse Mind & Body
Our approach is structured, medically supervised, and built around clarity — so you always know what’s happening and why.
1. Clinical Evaluation
Your care begins with a focused medical assessment that reviews your symptoms, treatment history, and goals, along with safety screening to determine the right clinical path.
2. Personalized Treatment Planning
If appropriate, your provider will recommend SPRAVATO® or ketamine therapy and outline how your care will work — including treatment frequency, expectations, and progress tracking.
3. In-Office Treatment With Monitoring
All sessions are performed in our New Rochelle clinic under direct medical supervision, with continuous vitals monitoring for safety and comfort.
4. Ongoing Optimization
Your plan is adjusted based on clinical response and tolerability, ensuring your care evolves as your needs change.
Why Rye Patients Choose Fuse
People aren’t looking for “a place that offers ketamine.” They’re looking for structured medical care that takes their condition seriously.
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Convenient access for Rye residents through our New Rochelle clinic
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Physician-led evaluations with clear candidacy standards
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Medically supervised, in-office treatment and monitoring
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A plan-driven approach so you always know what comes next
Getting Here From Rye, NY
Fuse Mind & Body is located in New Rochelle, making it a convenient option for Rye residents seeking SPRAVATO® (esketamine) or ketamine therapy without dealing with Manhattan traffic or long city commutes.
[Click here to get directions to our clinic.]
Important: You’ll need a ride home after SPRAVATO® sessions and, in many cases, after ketamine treatment depending on your individualized protocol. Please plan transportation in advance.
FAQs – SPRAVATO® & Ketamine Therapy Near Rye, NY
How quickly can SPRAVATO® or ketamine work?
Response varies by individual. Some Rye-area patients notice changes within days, while others improve more gradually over several weeks. Progress is tracked clinically rather than based on guesswork.
Do I need to stop my current antidepressant?
Not usually. SPRAVATO® is commonly used alongside an oral antidepressant. Your provider will review your current medications and coordinate your treatment safely.
Is SPRAVATO® the same as ketamine?
No. SPRAVATO® is an FDA-approved esketamine nasal spray prescribed for specific depressive conditions. Ketamine is a different medication and may be offered off-label under medical supervision.
How many sessions will I need?
Treatment plans are individualized. Most patients complete an initial treatment phase followed by maintenance care if they are responding well.
Do you also treat anxiety?
Many patients experience anxiety along with depression. Whether SPRAVATO® or ketamine is appropriate depends on your full clinical profile and is determined during evaluation.
Ready to Explore SPRAVATO® or Ketamine Therapy Near Rye, NY?
Schedule an evaluation with Fuse Mind & Body to determine whether you’re a candidate and what a personalized treatment plan could look like.
Call: 914-460-4891
Location: 175 Memorial Highway, Suite 1-1, New Rochelle, NY 10801
Request an appointment here.






