What Is IM Ketamine?
Intramuscular (IM) ketamine is administered as a single injection into a large muscle—typically the shoulder or thigh—for rapid absorption into the bloodstream. Originally developed as a surgical anesthetic, ketamine is now one of the most promising innovations in modern psychiatry. When given at sub-anesthetic doses, ketamine can help restore healthy neural activity and alleviate symptoms of depression and anxiety within hours
How IM Ketamine Works
Ketamine interacts with NMDA receptors in the brain to trigger a cascade of effects that support mood regulation and neural repair. This process increases glutamate signaling, enhances synaptogenesis (formation of new neural connections), and boosts communication within the prefrontal cortex—the region responsible for emotional balance and executive function.
Conditions Treated with IM Ketamine
IM ketamine therapy can benefit individuals struggling with treatment-resistant depression (TRD), major depressive disorder (MDD), PTSD, anxiety disorders, bipolar depression, OCD, and suicidal ideation. Our clinicians design individualized protocols tailored to your specific diagnosis and goals.
Treatment Type
Key Features
Efficacy
Cost & Coverage
Ideal For
Spravato
FDA-approved nasal spray
Similar benefits, slower onset
Insurance often covers
Non-injection preference
IV Ketamine
Continuous infusion
Gold-standard research base
Higher cost ($400–800/session)
Precise titration needs
IM Ketamine
Single injection, no IV required
Equivalent to IV
Lower cost; not covered by insurance
Rapid relief and simplicity
What to Expect During Your Treatment
Your journey begins with a comprehensive consultation and screening. During your session, ketamine is injected into the thigh or shoulder, taking effect within 5–10 minutes and lasting 30–60 minutes. You’ll be monitored for safety and remain for 45–60 minutes of observation afterward
Potential Side Effects
IM ketamine is generally well-tolerated. Temporary effects may include mild dizziness, nausea, dissociation, or increased heart rate. Most effects resolve within one hour under medical supervision.
Why Choose Fuse Mind & Body
Our physician-led team provides personalized dosing, compassionate care, and a serene environment designed for healing. Located in New Rochelle, NY, we proudly serve Westchester County and the surrounding metro area.
FAQs
How fast will I feel better?
Most patients notice improvement within 24–48 hours after one or two sessions.
How long do benefits last?
Relief often lasts from several days to weeks, with maintenance sessions extending results.
Can I drive afterward?
No. You must have a driver, as effects can linger for several hours.
Ready to Begin Your Healing Journey?
Discover how IM Ketamine therapy at Fuse Mind & Body can help you break through depression and rediscover balance.
Location:
175 Memorial Highway Suite 1-1 New Rochelle, NY 10801
Call Us: 914-460-4891
See if Ketamine Is Right For You
Life is hectic, and we get it. That’s why Fuse Mind & Body offers evening and weekend hours that work with your schedule. Our welcoming team is here to answer questions and provide guidance every step of the way as you begin your ketamine therapy journey.
